Search results for "perturbateur endocrinien"
showing 9 items of 9 documents
Early endocrine disruptors exposure acts on 3T3-L1 differentiation and endocrine activity
2017
International audience; Introduction: Data from last years suggested that early exposure to endocrine disruptors (EDs) can predispose newborns to endocrine dysfunction of adipocytes, obesity, and associated disorders. The implication of EDs at low doses on adipocyte development has been poorly investigated. For instance, vinclozolin (V) is a dicarboximide fungicide widely used in agriculture since the 90's, alone or in mixture with genistein (G), an isoflavonoid from Leguminosae. This study aims to identify the effect of vinclozolin alone or with genistein, on adipose tissue properties using cell culture.Methods: In steroid-free conditions, 3T3-L1 pre-adipocytes were induced to differentiat…
CIME: An integrative and multidisciplinary PNR-PE project on Chronic Impact of ED Mixture Exposure at environmental low doses on Reproduction, Develo…
2012
CIME: An integrative and multidisciplinary PNR-PE project on Chronic Impact of ED Mixture Exposure at environmental low doses on Reproduction, Development and Behavior. Colloque PNR-PE
Effect of three endocrine disruptors, bisphenol a, vinclozolin and genistein, on kallikrein 4 expression. – CIME project
2012
Effect of three endocrine disruptors, bisphenol a, vinclozolin and genistein, on kallikrein 4 expression. – CIME project. Colloque PNR-PE
Environmental levels of bisphenol A, genistein and vinclozolin feminize digit length ratios in male rats: towards a new sensitive indicator of prenat…
2012
Environmental levels of bisphenol A, genistein and vinclozolin feminize digit length ratios in male rats: towards a new sensitive indicator of prenatal endocrine disruption and its impact in the progeny. – CIME project. Colloque PNR-PE
Bisphenol A, genistein and vinclozolin: three endocrine disruptors which differentially affect the mammary gland in rats : critical window of exposure
2012
Bisphenol A, genistein and vinclozolin: three endocrine disruptors which differentially affect the mammary gland in rats : critical window of exposure. Colloque PNR-PE
Elaboration of a method to categorize substances of interest as regards to their potential endocrine disrupting activity: assessment and categorizati…
2021
EDCs are substances that alter function(s) of the endocrine system and consequently cause adverse health effects. The endocrine system consists of many cells and tissues that interact with each other and the rest of the body by means of hormones. This system is responsible for controlling a large number of processes in the body from gamete formation, to conception and early developmental processes such as organogenesis, and to most tissue and organ functions throughout life. EDCs interfere with endocrine function by many ways and, in doing so, lead to adverse effects on the health of humans and/or wildlife. Some of the observed health effects associated with EDCs include, butare not limited…
Submandibular salivary glands as an endocrine disruptor target: impact of the period of gensitein/vinclozolin exposure in the Rat
2012
Submandibular salivary glands as an endocrine disruptor target: impact of the period of gensitein/vinclozolin exposure in the Rat. Colloque PNR-PE
Analyse critique des résultats d’une étude de toxicité sur le développement du système nerveux ainsi que d’autres données publiées récemment sur les …
2010
Rapport d’expertise collective AFSSA; Analyse critique des résultats d’une étude de toxicité sur le développement du système nerveux ainsi que d’autres données publiées récemment sur les effets toxiques du bisphénol A
Exposition continue à des mélanges de perturbateurs endocriniens
2012
Dans ce projet, il est question d’explorer les effets de mélanges de perturbateurs endocriniens sur plusieurs générations, en considérant des cibles différentes (appareil reproducteur, glande mammaire, os, dent, tissu adipeux, glandes salivaires, cerveau...) et adaptées à chaque âge pour essayer de mieux comprendre comment agissent des perturbateurs endocriniens, en particulier ceux qui interfèrent avec les hormones sexuelles. Parmi les questions majeures que se pose le scientifique, figurent celles de l’effet d’une exposition prolongée à des mélanges de perturbateurs endocriniens depuis la conception jusqu’à l’âge adulte, et de la possibilité que ces expositions aient des répercussions sur…